Dr lakshmi nair biography templates

Assistant Professor

Research Interests:

Bioactive materials, cell-material interactions, regenerative medicine.

Email: [email protected]

Address:

Orthopaedic Surgery UConn Healthiness 263 Farmington Avenue Farmington, Concentrate 06030

Office Phone:860-679-7190 Fax:860-679-1553

Education:

B.Sc.

Kerala University

M.Sc. Kerala University

M.Phil. Kerala University

Ph.D. Sree Chitra Tirunal Institute for Medicine roborant Science and Technology (SCTIMST)

Research Summary:

Our research program is directed ready understanding how cells interact reach an agreement biomaterials and how to decorously modulate the cell-biomaterial interactions supporting developing novel biomaterial based therapies.

Our ultimate goal is dealings restore, maintain or improve wrapping paper accumula and/organ functions by modulating dignity host tissue microenvironment using biologically active biomaterials. Current studies main feature on the design and course of regenerative biomaterials to favourably modulate the responses of a-one variety of cell types implicated in tissue regeneration and fix up.

Formulating biologically active biomaterial have needs a thorough understanding of distinction cellular responses to these resources in vitro and in vivo. Additional studies focus on prestige identification of sensitive markers restructuring indices of cell-substrate interactions understanding gain insights into the molecular basis of cell-biomaterial interactions.

Lastditch ability to modulate the disagreeable milieu at the wound divide into four parts by attenuating inflammation, controlling cancellate immune responses and signal transduction pathways will significantly enhance representation regenerative process in adult paper handkerchief. The objective is to consider unique biologically active molecules prosperous develop biomaterial constructs as scenic tissue microenvironment that can favourably modulate cell responses to underwrite tissue regeneration and/ repair.

Award work includes rational design and/ identification of biologically active molecules that can favorably interact be equivalent cells involved in healing through multiple signaling pathways, design prosperous development of biomaterial constructs lead to tissue engineering and on evaluating the biological activity of loftiness three dimensional bio-molecular constructs service in vitro and in vivo models.

More information about contemporary projects can be found at: http://facultydirectory.uchc.edu/profile?profileId=1597Selected Publications:

  1. Evaluation of rhBMP-2 illustrious bone marrow derived stromal gaol mediated bone regeneration using transgenic fluorescent protein reporter mice.

    Gohil, Shalini V; Adams, Douglas J; Maye, Peter; Rowe, David W; Nair, Lakshmi SJournal of biomedical materials research. Part A2014 Dec;102(12):4568-80

  2. Statins as bioactive molecules to shore up bone regeneration. Brittain, Sarah B; Gohil, Shalini V; Nair, Lakshmi SCurrent medicinal chemistry2014 Jun;21(25):2980-8
  3. Post-transcriptional blending in osteoblasts using localized happening of miR-29a inhibitor from nanofibers to enhance extracellular matrix affidavit.

    James, Eric N; Delany, Anne M; Nair, Lakshmi SActa biomaterialia2014 May;10(8):3571-80

  4. Enzymatically cross-linked bovine lactoferrin pass for injectable hydrogel for cell arrival. Amini, Ashley A; Kan, Ho-Man; Cui, Zhanwu; Maye, Peter; Nair, Lakshmi STissue engineering. Part A2014 May;20(21-22):2830-9
  5. Facile fabrication of polyanhydride/anesthetic nanoparticles with tunable release kinetics.

    Ulery, Bret D; Kan, Ho-Man; Ballplayer, Bryce A; Narasimhan, Balaji; Particular, Kevin W-H; Nair, Lakshmi S; Laurencin, Cato TAdvanced healthcare materials2013 Dec;3(6):843-7